The performance of the apex-ultra® in the low-m/z region (150 – 2,000 m/z) is exceptional and does not suffer from complications of matrix background.
SmartBeam™ is also compatible with the full range of matrix choices for MALDI. The addition of the SmartBeam™ laser technology, developed initially for the Bruker Flex line of TOF/TOFs, creates a MALDI source that provides the necessary 200 Hz repetition rate laser and less than 40 micron spot size, as well as brilliant spectra quality. The MALDI source of the apex-ultra® is the Apollo II dual ESI/MALDI source based on the patented ion funnel technology, which provides the combination of high sensitivity with effortless changeover (one mouse-click) between ESI and MALDI. This new imaging solution promises to advance areas such as drug development and delivery, clinical and pathology research, as well as other areas of biological research such as lipidomics. The high sensitivity SmartBeam™ MALDI ion funnel source coupled with ultra-high mass resolution FTMS make the apex-ultra® ideally suited for tissue imaging of small molecules, including drugs from animals dosed at therapeutic levels, e.g. At Pittcon 2008, Bruker Daltonics announced the newest addition to its molecular imaging portfolio – the high performance apex-ultra® FTMS equipped with Bruker’s proprietary SmartBeam™ laser technology.